The Unit on Genome Structure and Regulation will start on April 30th at the National Institute of Child Health and Human Development (NICHD). We will be part of the Genetics and Epigenetics of Development Affinity Group.

To find out about how to reach us, please visit the Contact and Location section.

Our Research

Staining of a transverse section of an E7.5 mouse embryo with anti-beta Catenin (yellow) and  anti-Brachyury (orange) antibodies. Brachyury marks cells of the primitive streak undergoing epithelial to mesenchymal transition during the process of mesoderm formation (gastrulation).

Our lab is interested in understanding cell lineage differentiation, gene regulation and  how non-coding DNA elements and the 3D architecture of chromosomes contribute to these processes during development and disease. We are also fascinated with early-mammalian development as a system to decipher how cells make lineage decisions and how gene regulatory networks are established. Find out more about our research.

Hi-C and CTCF chip-seq data from human GM1278 cells. Data from GSE63525 (Rao et al.) visualized with HiGlass (Kerpedjiev et al.)

Find out who we are and see our publications

We want to do science in a laid-back and fun environment but with a rigorous, hard-working and imaginative attitude. We are big fans of sharing ideas and technologies, open science, collaborations and preprints. If this also appeals to you please